SFRP4

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SFRP4 protein abundance is significantly associated with the RNA expression of many other genes, with 18,896 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SFRP4-associated genes across cancer lineages are ISLR, PTGIS, and FNDC1. Each is linked with SFRP4 in more than 9 cancer types. Because this analysis shows association rather than direction, both SFRP4-to-partner and partner-to-SFRP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SFRP4 versus ISLR in CCRCC, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFRP4→partner) and Y-score (partner→SFRP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCISLR →+2.317+1.631<.001<.001310
OVPTGIS →+1.680+1.488<.001<.00139
OVFNDC1 →+1.446+1.109<.001<.00139
OVCOL3A1 →+2.255+1.432<.001<.00139
OVPRELP →+1.603+1.267<.001<.00139
CCRCCITGBL1 →+1.610+1.500<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,896 associations by consensus.

SFRP4 vs ISLR — CCRCC

Per-sample scatter of SFRP4 vs ISLR in CCRCC (Pearson r = 0.64).

Explore this scatter interactively →

Exploration