SFR1

Across TCGA cell cohorts, SFR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,762 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SFR1-associated GO terms across cancer lineages are DNA recombinase assembly, DNA repair complex assembly, and Meiotic nuclear division. Each is linked with SFR1 in more than 14 cancer types. Because this analysis shows association rather than direction, both SFR1-to-partner and partner-to-SFR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA recombinase assembly grouped by SFR1-low versus SFR1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SFR1→partner) and Y-score (partner→SFR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	DNA recombinase assembly →	+0.124	+0.828	<.001	<.001	3	15
LUNG_SCLC	DNA repair complex assembly →	+0.124	+0.828	<.001	<.001	3	15
BREAST	Meiotic nuclear division →	+0.057	+0.855	.002	.001	3	14
PANCREAS	Meiotic DNA recombinase assembly →	+0.142	+1.095	<.001	<.001	3	12
LIVER	Telomere capping →	+0.090	+1.310	.002	<.001	3	12
BLOOD_Lymphoma	Homologous recombination →	+0.087	+0.862	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,762 associations by consensus.

DNA recombinase assembly by SFR1 expression — LUNG_SCLC

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