SFPQ

Across TCGA patient cohorts, SFPQ protein abundance is significantly associated with the RNA expression of many other genes, with 18,824 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SFPQ-associated genes across cancer lineages are MBTD1, CHTOP, and FUBP1. Each is linked with SFPQ in more than 6 cancer types. Because this analysis shows association rather than direction, both SFPQ-to-partner and partner-to-SFPQ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SFPQ versus MBTD1 in HNSC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFPQ→partner) and Y-score (partner→SFPQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MBTD1 →	+0.542	+0.131	<.001	<.001	3	7
LSCC	CHTOP →	+0.451	+0.147	<.001	<.001	3	7
HNSC	FUBP1 →	+0.438	+0.135	<.001	<.001	3	7
UCEC	CLK2 →	+0.592	+0.134	<.001	<.001	3	7
HNSC	SNRPE →	+0.726	+0.140	<.001	<.001	3	7
BRCA	UBE2T →	+1.115	+0.195	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,824 associations by consensus.

SFPQ vs MBTD1 — HNSC

Explore this scatter interactively →