SFPQ

Across TCGA cell cohorts, SFPQ RNA expression is significantly associated with the go_rna of many other GO terms, with 5,365 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SFPQ-associated GO terms across cancer lineages are Double-strand break repair, DNA recombination, and Recombinational repair. Each is linked with SFPQ in more than 19 cancer types. Because this analysis shows association rather than direction, both SFPQ-to-partner and partner-to-SFPQ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Double-strand break repair grouped by SFPQ-low versus SFPQ-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SFPQ→partner) and Y-score (partner→SFPQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Double-strand break repair →	+0.097	+0.843	.001	.006	3	20
BONE	DNA recombination →	+0.112	+0.936	.001	.001	3	20
BONE	Recombinational repair →	+0.108	+0.836	.002	.009	3	20
BONE	Epigenetic regulation of gene expression →	+0.106	+1.080	<.001	<.001	3	20
OESOPHAGUS	DNA-templated DNA replication →	+0.107	+0.444	.002	.001	3	19
BONE	Regulation of DNA replication →	+0.109	+0.865	.002	.008	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,365 associations by consensus.

Double-strand break repair by SFPQ expression — BONE

Explore this box plot interactively →