SFMBT2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SFMBT2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,006 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SFMBT2-associated genes across cancer lineages are PPARD, HMGB1P17, and TRIM62. Each is linked with SFMBT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SFMBT2-to-partner and partner-to-SFMBT2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFMBT2→partner) and Y-score (partner→SFMBT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPPARD →-1.112-0.514<.001.00132
UCECHMGB1P17 →+0.811+0.471.003.00232
BRCATRIM62 →-0.869-0.671<.001<.00132
LSCCPSMF1 →-0.391-0.433.001.00532
LSCCOSBPL2 →-0.408-0.431.002.00432
LSCCMYO10 →-0.880-0.467<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,006 associations by consensus.

Exploration