Across TCGA cell cohorts, SFMBT2 mutation is significantly associated with the RNA expression of many other genes, with 94 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SFMBT2-associated genes across cancer lineages are ADAM7, GPX5, and C20orf85. Each is linked with SFMBT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SFMBT2-to-partner and partner-to-SFMBT2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFMBT2→partner) and Y-score (partner→SFMBT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ADAM7 →	+0.035	+4.922	<.001	.009	3	2
PANCREAS	GPX5 →	+0.022	+5.000	<.001	.006	3	1
BLOOD_Leukemia	C20orf85 →	+0.049	+5.969	<.001	.001	3	1
BLOOD_Leukemia	IL22 →	+0.050	+6.569	<.001	<.001	3	1
BLOOD_Leukemia	GPR26 →	+0.077	+5.539	<.001	.003	3	1
BLOOD_Leukemia	SCGB3A2 →	+0.144	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 94 associations by consensus.

Exploration

SFMBT2 survival (RNA) · tumor vs normal (RNA) · all SFMBT2 data types