SFMBT1

Across TCGA cell cohorts, SFMBT1 mutation is significantly associated with the drug of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SFMBT1-associated genes across cancer lineages are 630600, KIN001-042, and AZD7762. Each is linked with SFMBT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SFMBT1-to-partner and partner-to-SFMBT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 630600 grouped by SFMBT1-low versus SFMBT1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFMBT1→partner) and Y-score (partner→SFMBT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	630600 →	+0.624	+2.649	.045	.046	3	1
LARGE_INTESTINE	KIN001-042 →	+0.291	+2.652	.012	.045	3	1
LARGE_INTESTINE	AZD7762 →	+0.565	+2.646	.026	.047	1	1
LARGE_INTESTINE	MK-2206 →	+0.603	+2.646	.023	.047	1	1
LARGE_INTESTINE	Crizotinib →	+0.578	+2.646	.004	.047	1	1
LARGE_INTESTINE	IAP_5620 →	+0.383	+2.649	.037	.046	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

630600 by SFMBT1 expression — LARGE_INTESTINE

Explore this box plot interactively →