Across TCGA patient cohorts, SFI1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,236 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SFI1-associated genes across cancer lineages are LCMT2, SYCN, and DNAI1. Each is linked with SFI1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SFI1-to-partner and partner-to-SFI1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFI1→partner) and Y-score (partner→SFI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LCMT2 →	+0.970	+0.376	<.001	.002	3	2
UCEC	SYCN →	-0.301	-0.338	.002	.005	3	2
BRCA	DNAI1 →	+1.043	+0.551	<.001	.005	2	3
GBM	SPATA4 →	+0.359	+0.682	.007	.007	3	2
BRCA	TUBD1 →	+0.788	+0.639	.001	.002	3	2
GBM	MIS12 →	+0.367	+0.624	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,236 associations by consensus.

Exploration

SFI1 survival (RNA) · tumor vs normal (RNA) · all SFI1 data types