Across TCGA cell cohorts, SFI1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,110 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SFI1-associated GO terms across cancer lineages are Subtelomeric heterochromatin formation, Microtubule polymerization, and Telomere organization. Each is linked with SFI1 in more than 15 cancer types. Because this analysis shows association rather than direction, both SFI1-to-partner and partner-to-SFI1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SFI1→partner) and Y-score (partner→SFI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Subtelomeric heterochromatin formation →	+0.128	+1.305	<.001	<.001	3	16
BONE	Microtubule polymerization →	+0.108	+1.380	<.001	<.001	3	16
BONE	Telomere organization →	+0.076	+1.260	<.001	<.001	3	15
BONE	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.169	+1.092	<.001	.005	3	15
BONE	Negative regulation of chromosome condensation →	+0.174	+1.907	<.001	<.001	3	15
OESOPHAGUS	Flagellated sperm motility →	-0.136	-1.192	<.001	.005	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,110 associations by consensus.

Exploration

SFI1 survival (RNA) · tumor vs normal (RNA) · all SFI1 data types