SF3B6

Across TCGA patient cohorts, SF3B6 protein abundance is significantly associated with the RNA expression of many other genes, with 18,601 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SF3B6-associated genes across cancer lineages are UBE2S, FOXM1, and TTK. Each is linked with SF3B6 in more than 7 cancer types. Because this analysis shows association rather than direction, both SF3B6-to-partner and partner-to-SF3B6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SF3B6 versus UBE2S in BRCA, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SF3B6→partner) and Y-score (partner→SF3B6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	UBE2S →	+1.137	+0.248	.001	.002	3	7
BRCA	FOXM1 →	+1.337	+0.297	<.001	<.001	3	7
LSCC	TTK →	+1.010	+0.266	<.001	<.001	3	7
HNSC	DKC1 →	+0.820	+0.183	<.001	<.001	3	7
LSCC	NOL11 →	+0.664	+0.261	<.001	<.001	3	7
UCEC	CDCA8 →	+1.098	+0.156	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,601 associations by consensus.

SF3B6 vs UBE2S — BRCA

Explore this scatter interactively →