SF3B2

Across TCGA patient cohorts, SF3B2 protein abundance is significantly associated with the RNA expression of many other genes, with 18,782 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SF3B2-associated genes across cancer lineages are LIN9, CCNB1IP1, and SUV39H1. Each is linked with SF3B2 in more than 7 cancer types. Because this analysis shows association rather than direction, both SF3B2-to-partner and partner-to-SF3B2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SF3B2 versus LIN9 in OV, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SF3B2→partner) and Y-score (partner→SF3B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LIN9 →	+0.692	+0.234	<.001	<.001	3	8
UCEC	CCNB1IP1 →	+0.713	+0.157	<.001	<.001	3	7
UCEC	SUV39H1 →	+0.533	+0.161	<.001	.001	3	7
OV	DSE →	-0.788	-0.190	<.001	<.001	3	7
LSCC	CHTOP →	+0.466	+0.168	<.001	<.001	3	7
UCEC	SRSF2 →	+0.473	+0.180	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,782 associations by consensus.

SF3B2 vs LIN9 — OV

Explore this scatter interactively →