SF3A2

Across TCGA patient cohorts, SF3A2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,835 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SF3A2-associated proteins across cancer lineages are CHAF1B, CHAF1A_S141, and UHRF1. Each is linked with SF3A2 in more than 6 cancer types. Because this analysis shows association rather than direction, both SF3A2-to-partner and partner-to-SF3A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SF3A2 versus CHAF1B in GBM, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SF3A2→partner) and Y-score (partner→SF3A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CHAF1B →	+0.564	+0.501	<.001	<.001	3	7
LSCC	CHAF1A_S141 →	+0.773	+0.618	<.001	<.001	3	6
GBM	UHRF1 →	+0.695	+0.631	<.001	<.001	3	6
LSCC	CHAF1A →	+0.593	+0.565	<.001	<.001	3	6
GBM	WASHC4 →	-0.214	-0.470	<.001	<.001	3	5
GBM	SF3A3 →	+0.208	+0.463	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,835 associations by consensus.

SF3A2 vs CHAF1B — GBM

Explore this scatter interactively →