SF3A2

Across TCGA cell cohorts, SF3A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,097 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SF3A2-associated GO terms across cancer lineages are Regulation of protein localization to chromatin, Positive regulation of protein localization to chromatin, and Subtelomeric heterochromatin formation. Each is linked with SF3A2 in more than 15 cancer types. Because this analysis shows association rather than direction, both SF3A2-to-partner and partner-to-SF3A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to chromatin grouped by SF3A2-low versus SF3A2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SF3A2→partner) and Y-score (partner→SF3A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of protein localization to chromatin →	+0.143	+0.777	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Positive regulation of protein localization to chromatin →	+0.124	+0.808	.003	.006	3	15
BLOOD_Lymphoma	Subtelomeric heterochromatin formation →	+0.093	+0.659	<.001	<.001	3	15
BLOOD_Leukemia	Positive regulation of DNA replication →	+0.064	+0.462	<.001	<.001	3	14
BONE	U2-type prespliceosome assembly →	+0.116	+0.826	.001	<.001	3	14
BONE	Positive regulation of DNA metabolic process →	+0.077	+0.718	.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,097 associations by consensus.

Regulation of protein localization to chromatin by SF3A2 expression — URINARY_TRACT

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