SF3A1

Across TCGA patient cohorts, SF3A1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,794 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SF3A1-associated genes across cancer lineages are LINC01094, ILF2, and CCT3. Each is linked with SF3A1 in more than 7 cancer types. Because this analysis shows association rather than direction, both SF3A1-to-partner and partner-to-SF3A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SF3A1 versus LINC01094 in GBM, with a Pearson correlation of -0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SF3A1→partner) and Y-score (partner→SF3A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LINC01094 →	-0.748	-0.228	<.001	<.001	3	8
UCEC	ILF2 →	+0.920	+0.132	<.001	.002	3	7
UCEC	CCT3 →	+1.020	+0.149	<.001	<.001	3	7
GBM	S1PR1 →	-1.088	-0.321	<.001	<.001	3	7
OV	GAS5 →	+0.974	+0.246	<.001	<.001	3	7
HNSC	SRSF7 →	+0.651	+0.126	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,794 associations by consensus.

SF3A1 vs LINC01094 — GBM

Explore this scatter interactively →