SEZ6L2

Across TCGA patient cohorts, SEZ6L2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,933 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SEZ6L2-associated proteins across cancer lineages are CUTC, MKI67_S2708, and UBE2M. Each is linked with SEZ6L2 in more than 3 cancer types. Because this analysis shows association rather than direction, both SEZ6L2-to-partner and partner-to-SEZ6L2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEZ6L2 versus CUTC in HNSC, with a Pearson correlation of -0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SEZ6L2→partner) and Y-score (partner→SEZ6L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CUTC →	-0.314	-0.768	.001	.008	3	4
OV	MKI67_S2708 →	-1.073	-1.214	.006	.001	3	4
PDAC	UBE2M →	+0.203	+0.487	.002	.006	3	4
HNSC	PLOD3 →	+0.388	+1.097	<.001	<.001	3	3
HNSC	PRKCQ_T538 →	-0.593	-0.706	.008	.004	3	3
PDAC	PRKRA_S18 →	+0.420	+0.587	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,933 associations by consensus.

SEZ6L2 vs CUTC — HNSC

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