SEZ6L-AS1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, SEZ6L-AS1 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated SEZ6L-AS1 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher SEZ6L-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SEZ6L-AS1 expression acts as an unfavorable survival marker, although some lineages such as LGG show a favorable association.

STAD, ACC, and CESC are the cancer types where SEZ6L-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
STADOSTertileAll0.3120.598<.001102view →
ACCOSTertileIII,IV0.3900.821<.00184view →
CESCOSTertileIII,IV0.0910.755<.00172view →
UCECOSTertileAll0.7630.928<.00172view →
THYMOSTertileIII,IV0.2120.953.00936view →
SARCOSTertileAll0.0790.838<.00127view →
KIRCDFSTertileIV0.1270.630.03918view →
KIRPDFSTertileAll0.4520.870<.00118view →
BLCADFSTertileIII,IV0.1990.576.01118view →
COADDFSTertileIII,IV0.1870.653.00418view →
LGGOSQuartileAll0.6080.453.00310view →
PAADDFSTertileII,III,IV0.0790.438<.0019view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

Exploration