SETP9

Across TCGA pan-cancer cohorts, SETP9 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated SETP9 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SETP9 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated SETP9 expression acts as an unfavorable survival marker, although some lineages such as HNSC and CHOL show a favorable association.

HNSC, CHOL, and KICH are the cancer types where SETP9 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.761	0.653	.001	66	view →
CHOL	DFS	Quartile	All	0.901	0.241	<.001	58	view →
KICH	DFS	Tertile	All	0.043	0.971	<.001	54	view →
ACC	DFS	Tertile	IV	0.010	0.383	<.001	45	view →
SKCM	OS	Median	All	0.822	0.744	.002	37	view →
KIRP	DFS	Tertile	III,IV	0.175	0.629	.007	33	view →
THYM	OS	Median	All	1.000	0.733	.001	23	view →
CESC	OS	Median	All	0.908	0.841	.008	22	view →
BLCA	OS	Median	All	0.799	0.614	.015	21	view →
LUSC	DFS	Quartile	All	0.843	0.716	.007	17	view →
LAML	DFS	Median	All	0.448	0.685	.013	14	view →
BRCA	OS	Median	III,IV	0.947	0.867	.008	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

SETP9–HNSC (DFS)

Open the HNSC breakdown →