SETP7

Across TCGA patient cohorts, SETP7 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,429 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SETP7-associated GO terms across cancer lineages are Mitotic G2/M transition checkpoint, Maturation of LSU-rRNA, and rRNA metabolic process. Each is linked with SETP7 in more than 16 cancer types. Because this analysis shows association rather than direction, both SETP7-to-partner and partner-to-SETP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic G2/M transition checkpoint grouped by SETP7-low versus SETP7-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SETP7→partner) and Y-score (partner→SETP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Mitotic G2/M transition checkpoint →	+0.045	+0.135	.007	.005	1	17
STAD	Maturation of LSU-rRNA →	+0.051	+0.143	<.001	<.001	3	14
STAD	rRNA metabolic process →	+0.047	+0.129	<.001	<.001	3	14
STAD	Cell cycle G2/M phase transition →	+0.044	+0.135	<.001	<.001	3	14
STAD	Recombinational repair →	+0.039	+0.146	<.001	<.001	3	14
STAD	Centriole assembly →	+0.034	+0.127	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,429 associations by consensus.

Mitotic G2/M transition checkpoint by SETP7 expression — ESCA

Explore this box plot interactively →