SETP5

Across TCGA patient cohorts, SETP5 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,101 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SETP5-associated proteins across cancer lineages are WDR5, TOR1A, and GTF3C4. Each is linked with SETP5 in more than 3 cancer types. Because this analysis shows association rather than direction, both SETP5-to-partner and partner-to-SETP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SETP5 versus WDR5 in GBM, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SETP5→partner) and Y-score (partner→SETP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	WDR5 →	+0.217	+0.459	<.001	<.001	3	4
COAD	TOR1A →	+0.215	+0.193	<.001	.001	3	4
LSCC	GTF3C4 →	+0.255	+0.429	<.001	<.001	3	4
GBM	EHMT1 →	+0.414	+0.731	<.001	<.001	3	4
GBM	FUBP3 →	+0.148	+0.374	.001	.001	3	4
HNSC	WDR18 →	+0.229	+0.599	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,101 associations by consensus.

SETP5 vs WDR5 — GBM

Explore this scatter interactively →