SETP17

Across TCGA patient cohorts, SETP17 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,081 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SETP17-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, Regulation of transcription elongation by RNA polymerase II, and DNA-templated transcription elongation. Each is linked with SETP17 in more than 29 cancer types. Because this analysis shows association rather than direction, both SETP17-to-partner and partner-to-SETP17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by SETP17-low versus SETP17-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SETP17→partner) and Y-score (partner→SETP17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of gene expression, epigenetic →	+0.057	+0.207	<.001	<.001	3	30
ESCA	Regulation of transcription elongation by RNA polymerase II →	+0.072	+0.304	<.001	<.001	3	29
ESCA	DNA-templated transcription elongation →	+0.080	+0.286	<.001	<.001	3	28
ESCA	Positive regulation of viral process →	+0.067	+0.228	<.001	<.001	3	28
STAD	Regulation of DNA-templated transcription elongation →	+0.064	+0.202	<.001	<.001	3	28
ESCA	Positive regulation of DNA-templated transcription, elongation →	+0.074	+0.243	<.001	<.001	3	28

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,081 associations by consensus.

Negative regulation of gene expression, epigenetic by SETP17 expression — STAD

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