SETD3

Across TCGA patient cohorts, SETD3 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,917 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SETD3-associated proteins across cancer lineages are CDC42BPB, CEP170B, and UBR7. Each is linked with SETD3 in more than 7 cancer types. Because this analysis shows association rather than direction, both SETD3-to-partner and partner-to-SETD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SETD3 versus CDC42BPB in BRCA, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SETD3→partner) and Y-score (partner→SETD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CDC42BPB →	+0.359	+0.462	<.001	<.001	3	8
GBM	CEP170B →	+0.470	+0.183	<.001	.003	3	8
LSCC	UBR7 →	+0.381	+0.450	<.001	<.001	3	7
COAD	MARK3 →	+0.289	+0.399	<.001	<.001	3	7
OV	WDR20 →	+0.225	+0.312	<.001	<.001	3	7
LSCC	PPP4R3A →	+0.262	+0.382	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,917 associations by consensus.

SETD3 vs CDC42BPB — BRCA

Explore this scatter interactively →