SETD1B

Across TCGA patient cohorts, SETD1B RNA expression is significantly associated with the protein abundance of many other proteins, with 10,659 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SETD1B-associated proteins across cancer lineages are DDX23, PDE8A_S359, and RPL26. Each is linked with SETD1B in more than 3 cancer types. Because this analysis shows association rather than direction, both SETD1B-to-partner and partner-to-SETD1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SETD1B versus DDX23 in GBM, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SETD1B→partner) and Y-score (partner→SETD1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DDX23 →	+0.186	+0.328	.004	.006	3	4
CCRCC	PDE8A_S359 →	-0.920	-0.447	<.001	<.001	3	4
HNSC	RPL26 →	-0.349	-0.787	<.001	.002	3	3
LSCC	SART3 →	+0.176	+0.467	<.001	<.001	3	3
LSCC	SF3B3 →	+0.195	+0.495	.002	.002	3	3
LUAD	SIN3B_S740 →	+0.426	+0.404	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,659 associations by consensus.

SETD1B vs DDX23 — GBM

Explore this scatter interactively →