SET

Across TCGA patient cohorts, SET protein abundance is significantly associated with the RNA expression of many other genes, with 14,811 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SET-associated genes across cancer lineages are GLE1, GTF3C4, and NUP214. Each is linked with SET in more than 6 cancer types. Because this analysis shows association rather than direction, both SET-to-partner and partner-to-SET results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SET versus GLE1 in LSCC, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SET→partner) and Y-score (partner→SET) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GLE1 →	+0.658	+0.370	<.001	<.001	3	7
LSCC	GTF3C4 →	+0.696	+0.332	<.001	<.001	3	7
LSCC	NUP214 →	+0.589	+0.339	<.001	<.001	3	7
LSCC	MRRF →	+0.597	+0.389	<.001	<.001	3	7
LSCC	TMEM203 →	+0.514	+0.363	<.001	<.001	3	7
LSCC	NUP188 →	+0.650	+0.347	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,811 associations by consensus.

SET vs GLE1 — LSCC

Explore this scatter interactively →