Across TCGA patient cohorts, SESTD1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,553 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SESTD1-associated genes across cancer lineages are PALMD, PRPH2, and LAMP5. Each is linked with SESTD1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SESTD1-to-partner and partner-to-SESTD1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SESTD1→partner) and Y-score (partner→SESTD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PALMD →	+0.949	+0.284	<.001	<.001	3	6
HNSC	PRPH2 →	+0.624	+0.244	<.001	<.001	3	6
COAD	LAMP5 →	+1.534	+0.464	<.001	<.001	3	6
LSCC	KANK4 →	+1.341	+0.355	<.001	<.001	3	6
COAD	FXYD6 →	+0.970	+0.535	<.001	.001	3	6
HNSC	TPM1 →	+1.027	+0.310	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,553 associations by consensus.

Exploration

SESTD1 survival (RNA) · tumor vs normal (RNA) · all SESTD1 data types