Across TCGA cell cohorts, SESTD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,793 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SESTD1-associated GO terms across cancer lineages are Phosphatidylinositol biosynthetic process, Negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel, and Negative regulation of calcium ion transport. Each is linked with SESTD1 in more than 13 cancer types. Because this analysis shows association rather than direction, both SESTD1-to-partner and partner-to-SESTD1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SESTD1→partner) and Y-score (partner→SESTD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Phosphatidylinositol biosynthetic process →	+0.054	+1.485	.001	.001	3	14
BREAST	Negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel →	+0.253	+1.398	.005	<.001	3	13
URINARY_TRACT	Negative regulation of calcium ion transport →	+0.106	+1.793	.002	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of Golgi inheritance →	+0.147	+1.730	.008	.001	3	11
BONE	Cell-substrate junction organization →	+0.130	+1.143	<.001	<.001	3	10
BONE	Regulation of transforming growth factor beta receptor signaling pathway →	+0.067	+1.180	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,793 associations by consensus.

Exploration

SESTD1 survival (RNA) · tumor vs normal (RNA) · all SESTD1 data types