SESN3

Across TCGA patient cohorts, SESN3 protein abundance is significantly associated with the RNA expression of many other genes, with 3,236 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SESN3-associated genes across cancer lineages are ENDOD1, AMOT, and MPZL2. Each is linked with SESN3 in more than 3 cancer types. Because this analysis shows association rather than direction, both SESN3-to-partner and partner-to-SESN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SESN3 versus ENDOD1 in BRCA, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SESN3→partner) and Y-score (partner→SESN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ENDOD1 →	+1.016	+0.924	<.001	<.001	3	4
UCEC	AMOT →	+1.295	+0.578	<.001	<.001	3	3
HNSC	MPZL2 →	+1.031	+0.370	<.001	.005	2	4
BRCA	SRSF8 →	+0.596	+0.814	.001	.002	3	3
PDAC	GINS1 →	-1.282	-0.675	.009	.002	3	3
HNSC	ITM2B →	+0.667	+0.489	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,236 associations by consensus.

SESN3 vs ENDOD1 — BRCA

Explore this scatter interactively →