SESN2

Across TCGA patient cohorts, SESN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,356 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SESN2-associated proteins across cancer lineages are NDUFAF4, KIF1B, and LYPLA2. Each is linked with SESN2 in more than 3 cancer types. Because this analysis shows association rather than direction, both SESN2-to-partner and partner-to-SESN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SESN2 versus NDUFAF4 in BRCA, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SESN2→partner) and Y-score (partner→SESN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NDUFAF4 →	-0.471	-0.751	<.001	<.001	3	4
OV	KIF1B →	+0.241	+0.653	.009	.003	3	4
BRCA	LYPLA2 →	+0.270	+0.724	<.001	<.001	3	4
COAD	ZNF652_S57 →	-0.476	-0.486	<.001	.006	3	3
BRCA	STX12 →	+0.280	+0.572	.002	.001	3	3
UCEC	TARS2 →	-0.450	-0.864	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,356 associations by consensus.

SESN2 vs NDUFAF4 — BRCA

Explore this scatter interactively →