SESN2

Across TCGA patient cohorts, SESN2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,745 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SESN2-associated genes across cancer lineages are ABCC5, GLI2, and LINC02521. Each is linked with SESN2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SESN2-to-partner and partner-to-SESN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SESN2 versus ABCC5 in UCEC, with a Pearson correlation of -0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SESN2→partner) and Y-score (partner→SESN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ABCC5 →	-0.735	-0.490	<.001	<.001	3	3
UCEC	GLI2 →	-0.863	-0.489	.005	<.001	3	3
CCRCC	LINC02521 →	-0.377	-0.227	.005	.004	3	3
UCEC	BMP7 →	-1.526	-0.363	.001	.001	3	2
UCEC	COL1A1 →	-1.346	-0.449	<.001	.001	3	2
UCEC	LIN7A →	-1.182	-0.400	.005	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,745 associations by consensus.

SESN2 vs ABCC5 — UCEC

Explore this scatter interactively →