SERTM1

Across TCGA cell cohorts, SERTM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,870 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SERTM1-associated GO terms across cancer lineages are DNA-templated transcription initiation, Protein-RNA complex organization, and Nuclear transport. Each is linked with SERTM1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SERTM1-to-partner and partner-to-SERTM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by SERTM1-low versus SERTM1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERTM1→partner) and Y-score (partner→SERTM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA-templated transcription initiation →	+0.079	+1.985	<.001	.001	3	6
BONE	Protein-RNA complex organization →	+0.106	+2.210	<.001	<.001	3	6
BREAST	Nuclear transport →	+0.062	+0.040	<.001	.006	3	6
BREAST	Nucleocytoplasmic transport →	+0.062	+0.040	<.001	.006	3	6
LUNG_SCLC	Oxidative phosphorylation →	+0.104	+1.537	<.001	<.001	3	6
BONE	Regulation of cytoplasmic translation →	+0.126	+2.525	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,870 associations by consensus.

DNA-templated transcription initiation by SERTM1 expression — BONE

Explore this box plot interactively →