SERTAD3

Across TCGA cell cohorts, SERTAD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,837 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SERTAD3-associated GO terms across cancer lineages are Regulation of keratinocyte apoptotic process, Positive regulation of post-transcriptional gene silencing by RNA, and Regulation of binding. Each is linked with SERTAD3 in more than 10 cancer types. Because this analysis shows association rather than direction, both SERTAD3-to-partner and partner-to-SERTAD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of keratinocyte apoptotic process grouped by SERTAD3-low versus SERTAD3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERTAD3→partner) and Y-score (partner→SERTAD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of keratinocyte apoptotic process →	+0.152	+0.672	.002	<.001	3	11
SOFT_TISSUE	Positive regulation of post-transcriptional gene silencing by RNA →	+0.080	+0.651	.007	.004	3	10
STOMACH	Regulation of binding →	+0.056	+1.022	.003	.005	3	10
PANCREAS	Heparan sulfate proteoglycan catabolic process →	+0.156	+0.869	.004	<.001	3	10
SOFT_TISSUE	Positive regulation of post-transcriptional gene silencing →	+0.080	+0.651	.007	.004	3	10
STOMACH	Vacuole organization →	+0.050	+0.887	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,837 associations by consensus.

Regulation of keratinocyte apoptotic process by SERTAD3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →