SERTAD2

Across TCGA cell cohorts, SERTAD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,816 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SERTAD2-associated GO terms across cancer lineages are Regulation of hippo signaling, Cytosolic transport, and Phosphatidylinositol biosynthetic process. Each is linked with SERTAD2 in more than 12 cancer types. Because this analysis shows association rather than direction, both SERTAD2-to-partner and partner-to-SERTAD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of hippo signaling grouped by SERTAD2-low versus SERTAD2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERTAD2→partner) and Y-score (partner→SERTAD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of hippo signaling →	+0.086	+1.096	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.065	+0.961	.002	.002	3	12
BONE	Phosphatidylinositol biosynthetic process →	+0.064	+1.513	<.001	<.001	3	12
BONE	Regulation of stress-activated MAPK cascade →	+0.109	+1.230	.007	.005	3	12
BONE	Regulation of stress-activated protein kinase signaling cascade →	+0.116	+1.081	.001	.006	3	12
SOFT_TISSUE	Retrograde transport, endosome to Golgi →	+0.069	+0.961	.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,816 associations by consensus.

Regulation of hippo signaling by SERTAD2 expression — BREAST

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