SERPINI2

Across TCGA patient cohorts, SERPINI2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,256 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SERPINI2-associated proteins across cancer lineages are ZMYND10, NPHP4_S142, and WDR35. Each is linked with SERPINI2 in more than 4 cancer types. Because this analysis shows association rather than direction, both SERPINI2-to-partner and partner-to-SERPINI2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPINI2 versus ZMYND10 in OV, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINI2→partner) and Y-score (partner→SERPINI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ZMYND10 →	+1.230	+1.909	<.001	.001	3	5
PDAC	NPHP4_S142 →	+0.532	+2.656	<.001	<.001	3	5
UCEC	WDR35 →	+0.398	+1.683	<.001	<.001	3	4
HNSC	RFX5 →	+0.426	+0.809	<.001	<.001	3	4
UCEC	RFX2_S171 →	+1.211	+1.958	<.001	<.001	3	4
GBM	SPA17 →	+1.011	+1.206	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,256 associations by consensus.

SERPINI2 vs ZMYND10 — OV

Explore this scatter interactively →