SERPINI2

Across TCGA patient cohorts, SERPINI2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,919 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SERPINI2-associated genes across cancer lineages are SEC14L2, GGT1, and ESS2. Each is linked with SERPINI2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SERPINI2-to-partner and partner-to-SERPINI2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPINI2 versus SEC14L2 in PDAC, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINI2→partner) and Y-score (partner→SERPINI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SEC14L2 →	-0.392	-0.713	.003	.001	3	1
PDAC	GGT1 →	+0.401	+0.858	<.001	<.001	3	1
PDAC	ESS2 →	-0.179	-0.667	<.001	<.001	3	1
PDAC	SLC25A1 →	-0.351	-0.998	<.001	<.001	3	1
PDAC	LGALS2 →	+0.756	+0.768	<.001	<.001	3	1
PDAC	TRIOBP →	-0.251	-0.669	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,919 associations by consensus.

SERPINI2 vs SEC14L2 — PDAC

Explore this scatter interactively →