SERPINI2

Across TCGA cell cohorts, SERPINI2 RNA expression is significantly associated with the go_rna of many other GO terms, with 968 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SERPINI2-associated GO terms across cancer lineages are Post-translational protein targeting to endoplasmic reticulum membrane, Regulation of cell cycle G1/S phase transition, and Response to hypobaric hypoxia. Each is linked with SERPINI2 in more than 4 cancer types. Because this analysis shows association rather than direction, both SERPINI2-to-partner and partner-to-SERPINI2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Post-translational protein targeting to endoplasmic reticulum membrane grouped by SERPINI2-low versus SERPINI2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINI2→partner) and Y-score (partner→SERPINI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Post-translational protein targeting to endoplasmic reticulum membrane →	+0.049	+0.108	.004	.004	3	5
SOFT_TISSUE	Regulation of cell cycle G1/S phase transition →	+0.046	+0.160	<.001	.009	3	4
BONE	Response to hypobaric hypoxia →	+0.111	+0.023	.006	.008	3	4
BLOOD_Leukemia	Positive regulation of myeloid leukocyte mediated immunity →	+0.069	+0.606	<.001	<.001	3	4
BLOOD_Leukemia	Negative regulation of respiratory burst involved in inflammatory response →	+0.093	+0.824	.002	.004	3	4
BLOOD_Leukemia	Negative regulation of respiratory burst →	+0.093	+0.824	.002	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 968 associations by consensus.

Post-translational protein targeting to endoplasmic reticulum membrane by SERPINI2 expression — OVARY

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