SERPINI1

Across TCGA cell cohorts, SERPINI1 RNA expression is significantly associated with the RNA expression of many other genes, with 6,263 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SERPINI1-associated genes across cancer lineages are ZCWPW2, PDCD10, and GOLIM4. Each is linked with SERPINI1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SERPINI1-to-partner and partner-to-SERPINI1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPINI1 versus ZCWPW2 in OVARY, with a Pearson correlation of 0.41.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINI1→partner) and Y-score (partner→SERPINI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ZCWPW2 →	+0.423	+1.395	<.001	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	PDCD10 →	+0.867	+1.649	.001	.003	2	7
BLOOD_Leukemia	GOLIM4 →	+1.582	+1.624	<.001	<.001	3	5
LUNG_NSCLC_LUSC	ZNF711 →	+2.620	+4.351	.001	<.001	3	5
LUNG_NSCLC_LUSC	GDPD1 →	+1.819	+4.615	<.001	<.001	3	5
STOMACH	SPAST →	+0.784	+2.358	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,263 associations by consensus.

SERPINI1 vs ZCWPW2 — OVARY

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