SERPINH1

Across TCGA pan-cancer cohorts, SERPINH1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated SERPINH1 data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SERPINH1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SERPINH1 expression acts as an unfavorable survival marker.

CCRCC, LSCC, and PDAC are the cancer types where SERPINH1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	II,III,IV	0.228	0.979	.003	30	view →
LSCC	DFS	Tertile	II,III,IV	0.524	0.874	.005	15	view →
PDAC	OS	Tertile	All	0.646	0.929	.016	7	view →
COAD	DFS	Median	IV	0.493	0.944	.031	6	view →
GBM	DFS	Quartile	All	0.649	0.831	.007	4	view →
HNSC	DFS	Tertile	IV	0.514	0.817	.024	3	view →
UCEC	DFS	Tertile	All	0.757	0.920	.038	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

SERPINH1–CCRCC (OS)

Open the CCRCC breakdown →