SERPINH1

Across TCGA patient cohorts, SERPINH1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,306 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SERPINH1-associated genes across cancer lineages are CCN4, PCOLCE, and COL1A1. Each is linked with SERPINH1 in more than 9 cancer types. Because this analysis shows association rather than direction, both SERPINH1-to-partner and partner-to-SERPINH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPINH1 versus CCN4 in GBM, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINH1→partner) and Y-score (partner→SERPINH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CCN4 →	+1.492	+0.612	<.001	<.001	3	10
BRCA	PCOLCE →	+1.367	+0.741	<.001	<.001	3	10
GBM	COL1A1 →	+2.236	+0.607	<.001	<.001	3	10
LSCC	COL12A1 →	+1.788	+0.544	<.001	<.001	3	10
GBM	LAMA4 →	+0.978	+0.598	<.001	<.001	3	10
OV	SPARC →	+1.759	+0.696	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,306 associations by consensus.

SERPINH1 vs CCN4 — GBM

Explore this scatter interactively →