SERPINH1

Across TCGA patient cohorts, SERPINH1 mutation is significantly associated with the RNA expression of many other genes, with 988 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SERPINH1-associated genes across cancer lineages are LINC02500, ELOCP27, and RPL27P8. Each is linked with SERPINH1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SERPINH1-to-partner and partner-to-SERPINH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02500 grouped by SERPINH1-low versus SERPINH1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINH1→partner) and Y-score (partner→SERPINH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC02500 →	+0.114	+4.624	<.001	.005	3	3
CESC	ELOCP27 →	+0.206	+3.926	.008	.004	3	2
BLCA	RPL27P8 →	+0.613	+4.299	<.001	.007	3	2
SKCM	MIR4505 →	+0.350	+3.408	<.001	.009	3	2
SKCM	MIR7845 →	+0.309	+3.449	<.001	.009	3	1
SKCM	MIR8070 →	+0.332	+3.623	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 988 associations by consensus.

LINC02500 by SERPINH1 expression — SKCM

Explore this box plot interactively →