SERPINF2

Across TCGA patient cohorts, SERPINF2 mutation is significantly associated with the RNA expression of many other genes, with 438 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SERPINF2-associated genes across cancer lineages are RNU6-497P, RPS29P32, and TAF11L14. Each is linked with SERPINF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SERPINF2-to-partner and partner-to-SERPINF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-497P grouped by SERPINF2-low versus SERPINF2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINF2→partner) and Y-score (partner→SERPINF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-497P →	+0.451	+5.201	<.001	.007	3	2
UCEC	RPS29P32 →	+0.555	+2.599	<.001	.009	3	2
CESC	TAF11L14 →	+1.352	+5.010	<.001	.009	3	2
COAD	ARPP19P2 →	+0.297	+4.831	<.001	.003	3	2
LUSC	RNA5SP205 →	+0.255	+5.148	<.001	.002	3	2
UCEC	KCNJ2-AS1 →	-0.506	-3.459	.002	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 438 associations by consensus.

RNU6-497P by SERPINF2 expression — CESC

Explore this box plot interactively →