SERPINF2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SERPINF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,089 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible SERPINF2-associated GO terms across cancer lineages are Maintenance of blood vessel diameter homeostasis by renin-angiotensin, Regulation of hippocampal neuron apoptotic process, and Protein localization to synapse. Each is linked with SERPINF2 in more than 9 cancer types. Because this analysis shows association rather than direction, both SERPINF2-to-partner and partner-to-SERPINF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of blood vessel diameter homeostasis by renin-angiotensin grouped by SERPINF2-low versus SERPINF2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINF2→partner) and Y-score (partner→SERPINF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIVERMaintenance of blood vessel diameter homeostasis by renin-angiotensin →+1.523+3.591<.001<.001310
LUNG_NSCLC_LUSCRegulation of hippocampal neuron apoptotic process →+1.494+0.674.003.00237
SKINProtein localization to synapse →+0.104+0.297<.001.00137
STOMACHResponse to dexamethasone →+0.112+1.600.003.00937
LIVERKeratinocyte development →-0.511-5.080<.001<.00136
LIVERProtein O-linked glycosylation via fucose →-0.219-3.368.002.00336
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,089 associations by consensus.

Maintenance of blood vessel diameter homeostasis by renin-angiotensin by SERPINF2 expression — LIVER

Box plot of Maintenance of blood vessel diameter homeostasis by renin-angiotensin in SERPINF2-low vs SERPINF2-high samples in LIVER.

Explore this box plot interactively →

Exploration