SERPINF2

Across TCGA cell cohorts, SERPINF2 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SERPINF2-associated genes across cancer lineages are VAX1, TAFA1, and MINAR2. Each is linked with SERPINF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SERPINF2-to-partner and partner-to-SERPINF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VAX1 grouped by SERPINF2-low versus SERPINF2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINF2→partner) and Y-score (partner→SERPINF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	VAX1 →	+0.655	+3.285	<.001	.007	3	1
LARGE_INTESTINE	TAFA1 →	+0.209	+2.688	.003	.008	3	1
LARGE_INTESTINE	MINAR2 →	+0.027	+2.882	.003	.005	3	1
LARGE_INTESTINE	CRYBA4 →	+0.368	+3.626	.001	.003	3	1
LARGE_INTESTINE	DAZ2 →	+0.127	+3.678	.004	.001	3	1
LARGE_INTESTINE	F11 →	+0.037	+3.619	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

VAX1 by SERPINF2 expression — LARGE_INTESTINE

Explore this box plot interactively →