SERPIND1

Across TCGA patient cohorts, SERPIND1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,599 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SERPIND1-associated genes across cancer lineages are DIPK2B, LYVE1, and MYCT1. Each is linked with SERPIND1 in more than 8 cancer types. Because this analysis shows association rather than direction, both SERPIND1-to-partner and partner-to-SERPIND1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPIND1 versus DIPK2B in BRCA, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPIND1→partner) and Y-score (partner→SERPIND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DIPK2B →	+0.708	+0.582	<.001	<.001	3	9
HNSC	LYVE1 →	+1.136	+0.381	<.001	<.001	3	9
CCRCC	MYCT1 →	+0.840	+0.616	.001	<.001	3	8
CCRCC	KLF2 →	+0.953	+0.697	<.001	<.001	3	8
BRCA	ADGRL4 →	+0.751	+0.647	<.001	<.001	3	8
UCEC	EBF1 →	+0.846	+0.414	.004	.004	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,599 associations by consensus.

SERPIND1 vs DIPK2B — BRCA

Explore this scatter interactively →