SERPINB8

Across TCGA patient cohorts, SERPINB8 protein abundance is significantly associated with the RNA expression of many other genes, with 17,606 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SERPINB8-associated genes across cancer lineages are IFI16, PLAUR, and TGFBI. Each is linked with SERPINB8 in more than 7 cancer types. Because this analysis shows association rather than direction, both SERPINB8-to-partner and partner-to-SERPINB8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPINB8 versus IFI16 in COAD, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB8→partner) and Y-score (partner→SERPINB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	IFI16 →	+0.855	+0.278	<.001	.001	3	8
OV	PLAUR →	+1.185	+0.706	<.001	<.001	3	7
CCRCC	TGFBI →	+1.213	+0.355	<.001	<.001	3	7
GBM	TREM1 →	+1.416	+0.547	<.001	<.001	3	7
UCEC	PTPN22 →	+1.004	+0.470	<.001	<.001	3	7
GBM	EMP3 →	+0.799	+0.446	.003	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,606 associations by consensus.

SERPINB8 vs IFI16 — COAD

Explore this scatter interactively →