SERPINB8

Across TCGA cell cohorts, SERPINB8 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,914 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SERPINB8-associated GO terms across cancer lineages are Cellular response to abiotic stimulus, Cellular response to external stimulus, and Cellular response to environmental stimulus. Each is linked with SERPINB8 in more than 12 cancer types. Because this analysis shows association rather than direction, both SERPINB8-to-partner and partner-to-SERPINB8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to abiotic stimulus grouped by SERPINB8-low versus SERPINB8-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB8→partner) and Y-score (partner→SERPINB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cellular response to abiotic stimulus →	+0.058	+2.169	<.001	<.001	3	13
SOFT_TISSUE	Cellular response to external stimulus →	+0.129	+2.569	<.001	<.001	3	13
BONE	Cellular response to environmental stimulus →	+0.058	+2.169	<.001	<.001	3	13
LIVER	Cytoplasmic pattern recognition receptor signaling pathway →	+0.086	+1.749	.001	.002	3	12
LIVER	Urokinase plasminogen activator signaling pathway →	+1.544	+2.350	.001	<.001	3	12
LUNG_NSCLC_LUSC	Cell surface receptor signaling pathway via STAT →	+0.075	+1.395	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,914 associations by consensus.

Cellular response to abiotic stimulus by SERPINB8 expression — BONE

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