SERPINB7

Across TCGA patient cohorts, SERPINB7 protein abundance is significantly associated with the RNA expression of many other genes, with 10,498 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SERPINB7-associated genes across cancer lineages are LOX, COL5A2, and LGALS1. Each is linked with SERPINB7 in more than 6 cancer types. Because this analysis shows association rather than direction, both SERPINB7-to-partner and partner-to-SERPINB7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPINB7 versus LOX in OV, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB7→partner) and Y-score (partner→SERPINB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LOX →	+1.558	+1.455	<.001	<.001	3	7
OV	COL5A2 →	+1.697	+1.617	<.001	<.001	3	7
GBM	LGALS1 →	+0.782	+0.655	<.001	.001	3	6
OV	SPARC →	+1.297	+1.171	<.001	<.001	3	6
BRCA	MFAP2 →	+1.276	+0.760	<.001	<.001	3	6
OV	GLT8D2 →	+1.102	+1.049	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,498 associations by consensus.

SERPINB7 vs LOX — OV

Explore this scatter interactively →