SERPINB7

Across TCGA patient cohorts, SERPINB7 mutation is significantly associated with the RNA expression of many other genes, with 2,327 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SERPINB7-associated genes across cancer lineages are RBM18, MSANTD3, and OR6B1. Each is linked with SERPINB7 in more than 2 cancer types. Because this analysis shows association rather than direction, both SERPINB7-to-partner and partner-to-SERPINB7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBM18 grouped by SERPINB7-low versus SERPINB7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB7→partner) and Y-score (partner→SERPINB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RBM18 →	+0.395	+2.716	.006	.003	3	3
UCEC	MSANTD3 →	+0.570	+3.016	<.001	<.001	3	3
BLCA	OR6B1 →	+0.057	+4.704	<.001	.005	3	3
BLCA	GARS1P1 →	+0.087	+5.173	<.001	<.001	3	2
BLCA	MIR3919 →	+0.407	+5.229	<.001	.002	3	2
BLCA	MIR3121 →	+0.618	+4.704	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,327 associations by consensus.

RBM18 by SERPINB7 expression — UCEC

Explore this box plot interactively →