SERPINB7

Across TCGA cell cohorts, SERPINB7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,684 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SERPINB7-associated GO terms across cancer lineages are Blood coagulation, intrinsic pathway, Wound healing, and Blood coagulation, fibrin clot formation. Each is linked with SERPINB7 in more than 13 cancer types. Because this analysis shows association rather than direction, both SERPINB7-to-partner and partner-to-SERPINB7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Blood coagulation, intrinsic pathway grouped by SERPINB7-low versus SERPINB7-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB7→partner) and Y-score (partner→SERPINB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Blood coagulation, intrinsic pathway →	+0.407	+2.707	.001	.009	3	14
BONE	Wound healing →	+0.132	+3.423	<.001	<.001	3	13
STOMACH	Blood coagulation, fibrin clot formation →	+0.351	+3.496	.001	.001	3	12
BREAST	Regulation of protein localization to mitochondrion →	+0.134	+2.117	<.001	<.001	3	11
BONE	Regulation of plasma membrane repair →	+0.360	+3.157	<.001	<.001	3	11
LIVER	Positive regulation of extrinsic apoptotic signaling pathway →	+0.151	+3.072	<.001	.002	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,684 associations by consensus.

Blood coagulation, intrinsic pathway by SERPINB7 expression — LUNG_NSCLC_LUSC

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