SERPINB6

Across TCGA patient cohorts, SERPINB6 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,889 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SERPINB6-associated proteins across cancer lineages are RIPK1, SERPINB1, and TOP1. Each is linked with SERPINB6 in more than 6 cancer types. Because this analysis shows association rather than direction, both SERPINB6-to-partner and partner-to-SERPINB6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPINB6 versus RIPK1 in OV, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB6→partner) and Y-score (partner→SERPINB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RIPK1 →	+0.395	+0.791	<.001	<.001	3	6
OV	SERPINB1 →	+0.606	+0.774	<.001	<.001	2	7
BRCA	TOP1 →	-0.341	-0.538	<.001	<.001	3	4
GBM	INF2 →	+0.298	+0.335	.003	.008	3	4
GBM	ITGA3 →	+0.734	+0.370	<.001	.001	3	4
GBM	ARHGAP18 →	+0.395	+0.408	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,889 associations by consensus.

SERPINB6 vs RIPK1 — OV

Explore this scatter interactively →