SERPINB6

Across TCGA patient cohorts, SERPINB6 protein abundance is significantly associated with the RNA expression of many other genes, with 13,947 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SERPINB6-associated genes across cancer lineages are LHFPL6, CENPF, and IGFBP7. Each is linked with SERPINB6 in more than 7 cancer types. Because this analysis shows association rather than direction, both SERPINB6-to-partner and partner-to-SERPINB6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPINB6 versus LHFPL6 in BRCA, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB6→partner) and Y-score (partner→SERPINB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LHFPL6 →	+0.932	+0.385	.001	.001	3	8
LUAD	CENPF →	-1.072	-0.302	<.001	<.001	3	7
UCEC	IGFBP7 →	+0.967	+0.394	<.001	<.001	3	7
LUAD	TRIP13 →	-1.036	-0.233	<.001	<.001	3	7
UCEC	FAM83D →	-1.336	-0.503	<.001	<.001	3	6
BRCA	AUNIP →	-0.866	-0.387	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,947 associations by consensus.

SERPINB6 vs LHFPL6 — BRCA

Explore this scatter interactively →