SERPINB6

Across TCGA patient cohorts, SERPINB6 protein abundance is significantly associated with the protein abundance of many other proteins, with 29,915 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SERPINB6-associated proteins across cancer lineages are SERPINB1, ILK, and UBTF_S484. Each is linked with SERPINB6 in more than 8 cancer types. Because this analysis shows association rather than direction, both SERPINB6-to-partner and partner-to-SERPINB6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPINB6 versus SERPINB1 in GBM, with a Pearson correlation of 0.41.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB6→partner) and Y-score (partner→SERPINB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SERPINB1 →	+0.563	+0.414	<.001	<.001	3	9
UCEC	ILK →	+0.476	+0.283	<.001	<.001	3	8
BRCA	UBTF_S484 →	-0.853	-0.366	<.001	<.001	3	8
BRCA	DDX18 →	-0.416	-0.445	<.001	<.001	3	8
UCEC	EHD2 →	+1.134	+0.425	<.001	<.001	3	8
UCEC	KANK2 →	+0.992	+0.412	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 29,915 associations by consensus.

SERPINB6 vs SERPINB1 — GBM

Explore this scatter interactively →